A massive manhunt is underway as police search for the culprits of a mass shooting that killed four people in Alabama overnight.

Gunfire erupted at Five Points South cigar lounge in Birmingham just after 11pm on Saturday night – injuring at least 22 people and killing four.

Ellen Sweeney, 39, Thomas Sweeney senior, 43, and Thomas Sweeney junior, 18, have reportedly fled to the Republic of Ireland with a judge yesterday calling for Interpol to intervene.

MAILONLINE BLOG: Follow live coverage as Hezbollah vows to respond to a deadly pager bomb attack it says was carried out by Israel.

The horror crash happened in the city of Zagazig, the capital of Sharqiya province, the country’s railway authority said in a statement.

At least 11 Palestinians have been killed, according to local health officials, including five in an air strike on the al-Far’a refugee camp, and six in a drone strike and armed clashes in Jenin.

The customers reportedly bought the illegal liquor contaminated with methanol and isopropanol from street stalls in Bangkok before suffering dizziness, breathing difficulties, and vomiting.

Among the dead were a Russian couple who were on holiday in the area, local police chief Khundech Na Nongkhai said, adding that officers were working to identify the other victims.

The Duke and Duchess of Sussex spent four days visiting Colombia in their second tour after flying to Nigeria earlier this year.