US pharmaceutical giant Pfizer has increased its bid for British rival AstraZeneca to £69.3 billion. The company has offered the board of the British company £55-a-share in what it is describing as its final offer.

Bernard McSorley (pictured) stabbed Paul McDonagh in the back with a Stanley knife in Lancaster, saying: ‘You’re a dead man.’

The Palestinian split goes back to 2007 when the Islamic militant group Hamas seized Gaza from the Western-backed Abbas, leaving him with only parts of the West Bank. The split weakened Abbas' position in peace talks with Israel. Just before the latest …

PANAMA CITY (AP) — Panamanians delivered a rebuke to President Ricardo Martinelli's attempt to extend his grip on power, electing as his successor a former ally turned rival in one of the toughest-fought contests since democracy was restored two decades ago.

The disappearance of Malaysia Airlines Flight 370 has generated dozens of theories on where it is now, from the Indian Ocean to the South China Sea, and how it vanished. Here's a rundown of what we know and what we don't, along with clues and theories about what happened to the Boeing 777 jetliner:

Watchdog Ofgem called on the Big Six suppliers to ‘do the right thing’ and return the cash to 3.5million families and 300,00 businesses.

SIMFEROPOL, Ukraine (AP) — Fistfights broke out between pro- and anti-Russian demonstrators in Ukraine's strategic Crimea region on Wednesday as Russian President Vladimir Putin reportedly ordered tests of the combat readiness of troops just across the border.

Hundreds of thousands of Venezuelans took to the streets of Caracas in marches for and against President Nicolas Maduro’s government Saturday, as the nation’s massive divide became ever more evident. The protests — which began on February 4 — are seen as the biggest test yet to socialist leader Maduro since he succeeded late leftist […]

Prime Instant Video combines LoveFilm Instant with Amazon Prime for £79 a year. It’s already available in the U.S. and launches in the UK and Germany next week.

WARNING: GRAPHIC CONTENT: The amateur video shows members of the Islamic State in Iraq and Levant shooting seven more moderate rebels in the head in the town of Atarib.